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Newly Available Datasets

The HEAL Data Platform connects to HEAL-compliant repositories where data are stored, providing a single point of access to the diverse array of studies and data funded by the NIH HEAL Initiative®. Here are some of the latest studies to share their data so that they are accessible on the HEAL Data Platform.

October - December 2024

Targeting sensory ganglia and glial signaling for the treatment of acute and chronic pain

TEMUGIN BERTA; UNIVERSITY OF CINCINNATI

High-Resolution, Spinal Cord Stimulation for Non-Opioid Treatment of Neuropathic Pain

BRYAN L MCLAUGHLIN; MICRO-LEADS, INC.

Profiling the human gut microbiome for potential analgesic bacterial therapies

JACK ANTHONY GILBERT, PHILIP PETER STRANDWITZ; HOLOBIOME, INC.

Testing an occupational stress intervention for harm reduction workers in substance misuse settings

SUZANNAH K CREECH; UNIVERSITY OF TEXAS AT AUSTIN

Data Coordinating Center for the NICHD Neonatal Research Network (U24)

ABHIK DAS; RESEARCH TRIANGLE INSTITUTE

Examining Trauma Prevalence and Exploring Interoception as a Mechanism of Emotion Regulation in MOUD

JOSEPH O MERRILL, CYNTHIA J PRICE; UNIVERSITY OF WASHINGTON

Risk of Care Escalation after Non-Pharmacologic Treatment: Leveraging Real World Physical Therapy Data

TREVOR LENTZ; DUKE UNIVERSITY

Targeting GPCRs in amygdalar and cortical neural ensembles to treat pain aversion

GREGORY SCHERRER; UNIV OF NORTH CAROLINA CHAPEL HILL

Equity Using Interventions for Pain and Depression (EQUIPD)

MARIANNE MATTHIAS; INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS

Integrating Nonpharmacologic Strategies for Pain with Inclusion, Respect, and Equity (INSPIRE): Tailored digital tools, telehealth coaching, and primary care coordination

JASON M SATTERFIELD; UNIVERSITY OF CALIFORNIA, SAN FRANCISCO

Validation of a novel cortical biomarker signature for pain

JOYCE TEIXEIRA DA SILVA, SIOBHAN SCHABRUN, DAVID SEMINOWICZ; UNIVERSITY OF MARYLAND BALTIMORE

Safety, pharmacokinetics and efficacy of extended-release naltrexone in pregnant women with opioid use disorder

ELISHA WACHMAN; BOSTON MEDICAL CENTER

July - September 2024

Targeting Endosomal Receptors for Treatment of Chronic Pain

NIGEL W BUNNETT, BRIAN L SCHMIDT; NEW YORK UNIVERSITY

Validation of Fibroblast-Derived PI16 as a Novel Target for pain Treatment

ANDREW JOHN SHEPHERD; UNIVERSITY OF TX MD ANDERSON CAN CTR

Sympathetic-mediated sensory neuron cluster firing as a novel therapeutic target for neuropathic pain

XINZHONG DONG, JUN-MING ZHANG; JOHNS HOPKINS UNIVERSITY

Novel Implantable Device to Negate Post-Amputation Pain

SANDEEP KATHJU, MOHAMED E LABIB; NOVAFLUX, INC.

Target validation of a novel CGRP receptor in migraine

DEBBIE L HAY, ANDREW F RUSSO; UNIVERSITY OF IOWA

Disrupting ion channel scaffolding to treat neuropathic pain

ARINDAM BHATTACHARJEE; STATE UNIVERSITY OF NEW YORK AT BUFFALO

Clinical Translation of Ultrasonic Ketamine Uncaging for Non-Opioid Therapy of Chronic Pain

RAAG D AIRAN, NOLAN R. WILLIAMS; STANFORD UNIVERSITY

tDCS to decrease opioid relapse

ANA M ABRANTES, MICHAEL D STEIN; BUTLER HOSPITAL (PROVIDENCE, RI)

Latinx Children and Surgery

ZEEV KAIN; UNIVERSITY OF CALIFORNIA-IRVINE

Tracking the opioid epidemic with social media: an early warning system

RUSS BIAGIO ALTMAN; STANFORD UNIVERSITY

A Novel Assay to Improve Translation in Analgesic Drug Development

SIDNEY S NEGUS; VIRGINIA COMMONWEALTH UNIVERSITY

Accelerator Strategies for States to Improve System Transformations Affecting Children, Youth and Families

KIMBERLY E. HOAGWOOD, MARY MCKERNAN MCKAY; NEW YORK UNIVERSITY SCHOOL OF MEDICINE

April - June 2024

Smartphone-based rewards as a bridge to treatment for naloxone reversal patients

ANTHONY DEFULIO; DYNAMICARE HEALTH, INC.

Collaborative Care Office-Based Opioid Treatment for Adolescents and Young Adults

SCOTT EVAN HADLAND; BOSTON MEDICAL CENTER

Improving Access and Treatment for Co-occurring Opioid Use Disorders and Mental Illness

MIRIAM KOMAROMY, KATHERINE E WATKINS; RAND CORPORATION

Reducing Stigma Toward People with Opioid Use Disorder Among Primary Care Clinicians

STEPHANIE A. HOOKER, GAVIN BART, REBECCA ROSSOM; HEALTH PARTNERS INSTITUTE FOR EDUCATION & RESEARCH

Multi-organ-on-chip device for modeling opioid reinforcement and withdrawal and the negative affective component of pain: a therapeutic screening tool.

NUREDDIN ASHAMMAKHI, ALI KHADEMHOSSEINI, NIGEL T MAIDMENT, CLIVE NIELS SVENDSEN, STEPHANIE KRISTIN SEIDLITS; UNIVERSITY OF CALIFORNIA LOS ANGELES

Development of an MRgFUS system for precision-targeted neuromodulation of pain circuits with simultaneous functional MRI

CHARLES F CASKEY, LI MIN CHEN, WILLIAM A GRISSOM; VANDERBILT UNIVERSITY MEDICAL CENTER

Evaluation of drug mixtures for treating pain: behavioral and pharmacological interactions between opioids and serotonin agonists

DAVID RICHARD MAGUIRE; UNIVERSITY OF TEXAS HLTH SCIENCE CENTER

Researching Effective Strategies to Prevent Opioid Death (RESPOND)

BENJAMIN P. LINAS; BOSTON MEDICAL CENTER

Validation of Targeting Macrophage-Mediated Events in the DRG to Alleviate Chronic Spinal Cord Injury Pain

MEGAN R DETLOFF; DREXEL UNIVERSITY

Development & Malleability from Childhood to Adulthood

NICHOLAS S IALONGO; JOHNS HOPKINS UNIVERSITY

Effect of Mindfulness Training on Opioid Use and Anxiety During Primary Care Buprenorphine Treatment

ZEV DAVID SCHUMAN OLIVIER; CAMBRIDGE HEALTH ALLIANCE

Human Nociceptor and Spinal Cord Molecular Signature Center

MICHELE CURATOLO, PATRICK M DOUGHERTY, THEODORE J PRICE; UNIVERSITY OF TEXAS DALLAS

Addressing the chronic pain epidemic among older adults in underserved community center; The GetActive+ study.

CHRISTINE S RITCHIE, ANA-MARIA VRANCEANU; MASSACHUSETTS GENERAL HOSPITAL

Assessing chronic pain using brain entropy mapping

ZE WANG; UNIVERSITY OF MARYLAND BALTIMORE

PNPase inhibition as an effective treatment for chronic bladder pain

LORI A BIRDER, EDWIN KERRY JACKSON; UNIVERSITY OF PITTSBURGH AT PITTSBURGH

Nociceptive Afferent Topographical Innervation of the Heart and Stomach

ZIXI JACK CHENG; UNIVERSITY OF CENTRAL FLORIDA

Validation of a Community Pharmacy-based Prescription Drug Monitoring Program Risk Screening Tool (PHARMSCREEN)

GERALD COCHRAN, T. JOHN WINHUSEN; UNIVERSITY OF UTAH HEALTH

January - March 2024

ECHO Administrative Supplement - Neonatal Opioid Trials

LAURA KRISTIN NEWBY, PHILLIP BRIAN SMITH; DREXEL UNIVERSITY

Process Development, Manufacturing, and Preclinical Evaluation of a Monoclonal Antibody for Fentanyl Overdose

PAUL T BREMER; CESSATION THERAPEUTICS, LLC

Treating pain in sickle cell disease by means of focused ultrasound neuromodulation

BIN HE; CARNEGIE-MELLON UNIVERSITY

Regulation of neuropathic pain by exercise: effects on nociceptor plasticity and inflammation

MEGAN R DETLOFF; DREXEL UNIVERSITY

Multi-organ human-on-a-chip system to address overdose and acute and chronic efficacy and off-target toxicity

JAMES J HICKMAN, MICHAEL L SHULER; UNIVERSITY OF CENTRAL FLORIDA

Modeling temporomandibular joint disorders pain: role of transient receptor potential ion channels

YONG CHEN; DUKE UNIVERSITY

Collaborating to Heal Addiction and Mental Health in Primary care (CHAMP)

JOHN C. FORTNEY, ANNA RATZLIFF, ANDREW J SAXON; UNIVERSITY OF WASHINGTON

Sleep, opiate withdrawal and the N/OFQ - NOP system

MICHAEL R BRUCHAS, THOMAS S KILDUFF; SRI INTERNATIONAL

Improving health and employment outcomes through workplace opioid policies

ANN MARIE DALE; WASHINGTON UNIVERSITY